• Zaleha Md Isa Faculty of Medicine, Universiti Kebangsaan Malaysia
  • Afraah Amani Anuar Faculty of Medicine, Universiti Kebangsaan Malaysia
  • Amirul Danial Azmi Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, 56000 Kuala Lumpur, Malaysia.
  • Sanjeevaraj Tamil Selvan Faculty of Medicine, Universiti Kebangsaan Malaysia
  • Noor Shafiqah Hisham Faculty of Medicine, Universiti Kebangsaan Malaysia
  • Yong Zi Qing Faculty of Medicine, Universiti Kebangsaan Malaysia



Caffeine, 1,3,7-trimethylxanthine, mental health, medical students


Caffeine (1,3,7-trimethylxanthine) consumption among students is known to increase alertness and energy, as well as to alleviate stress. There has been an increase of caffeine consumption amongst young adults. Currently, there are no studies regarding caffeine consumption and its influence on mental health among Malaysians. We aimed to determine the relationship of caffeine consumption with depression, anxiety and stress among medical students. A cross sectional study was conducted among medical students in the Faculty of Medicine, Universiti Kebangsaan Malaysia. Data were collected via an online survey using two questionnaires, namely the semi-quantitative Food Frequency Questionnaires on Caffeine Intake and Depression, Anxiety and Stress Scale (DASS-21). A total of 262 medical students completed the survey. The prevalence of depression, anxiety and stress was 9.2%, 16.8% and 1.1%, respectively. Majority of students (98.5%) consumed caffeine from coffee, tea, soft drinks, energy drinks and chocolate drinks/food. The median daily caffeine consumption among consumers was 67.98 (25th,75th percentile: 24.83, 139.71) mg/day. There was a significant association between race and anxiety (p=0.038) in which the Malay students had the highest prevalence (21.1%), followed by Indian (16.1%), other races (15.4%) and Chinese students (3.8%). Caffeine consumption did not influence mental health of medical students in this study. Anxiety is the most prominent mental health problem among them. We recommend a programme tailored to medical students in recognising symptoms of mental health problems so that early intervention can be carried out.


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How to Cite

Md Isa, Z., Anuar, A. A. ., Danial Azmi, A. ., Sanjeevaraj Tamil Selvan, Hisham, N. S., & Yong Zi Qing. (2021). DOES CAFFEINE INTAKE INFLUENCE MENTAL HEALTH OF MEDICAL STUDENTS?. Malaysian Journal of Public Health Medicine, 21(2), 22–28.