ASSOCIATED RISK FACTORS OF ACUTE MYOCARDIAL INFARCTION AMONG HUNAN POPULATION IN CHINA
AMI and Hunan
The purpose of this study to determine the clinical characteristic of the associated risk factors of acute myocardial infarction patients (AMI) among the Hunan Han population in China. The retrospectively collected the records data of 595 both STEMI and NSTEMI patients from the first Xiangya hospital, Hunan, China over a period of January 2018 and December 2018. These studies revealed clinical characteristics with associated risk factors among acute myocardial infarction patients. A total of 595 diagnosed acute myocardial infarction patients participated in this study among males 70.9% and females 29% with mean age e 52.9+11.3 years. While 90% had STEMI and 9.9 % had NSTEMI. The chest pain 94.4%, 86% and shortness of breath 55%, 100% presented with STEMI and NSTEMI groups respectively. Smoking incidence in male subject 70.3% had higher than in female subject 29.1 % (P<0.05). Hypertension and diabetes mellitus found 59%, 69.5% in male participants as compared to 40.6%, 30.4% in female participants respectively (P<0.05). However, no statistical difference was found among dyslipidemia males 48.6% and females 47.4%. The most common type of AMI was STEMI and usually presented with chest pain and shortness of breath. The AMI patients were more found in male and common associated risk factors were smoking and hypertension followed by diabetes mellitus and dyslipidemia.
2. Cao CF, Ren JY, Zhou XH etal. Twenty-year trends in major cardiovascular risk factors in hospitalized patients with acute myocardial infarction in Beijing. Chin Med J. 2013; 126:4210–5.
3. Yang G, Wang Y, Zeng Y, et al. Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet. 2013; 381:1987–2015.
4. Chen WW, Gao RL, Liu LS, et al. China cardiovascular diseases report 2015: a summary. J Geriatr Cardiol. 2017; 14:1-10.
5. GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018; 392:1736-88.
6. Lim SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012; 380:2224-60.
7. Zhang G, Yu C, Zhou M, et al. Burden of Ischemic heart disease and attributable risk factors in China from 1990 to 2015: findings from the global burden of disease 2015 study. BMC Cardiovasc Disord. 2018; 18:18.
8. Sehestedt T, Hansen TW, Li Y, et al. Are blood pressure and diabetes additive or synergistic risk factors? Outcome in 8494 subjects randomly recruited from 10 populations. Hypertens Res. 2011; 34:714-21.
9. Serap Tutgun Onrat ,O nder Akci , Zafer So ylemez etal Prevalence of myocardial infarction polymorphisms in Afyonkarahisar, Western Turkey. Mol Biol Rep. 2012; 39:9257–9264.
10. Gajalakshmi V, Peto R, Kanaka TS etal. Smoking and mortality from tuberculosis and other diseases in India: retrospective study of 43000 adult male deaths and 35000 controls. Lancet. 2003; 362:507–15.
11. Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004; 364:937–52.
12. Jing Li, Xi Li, Qing Wang, Shuang Hu etal. ST-segment elevation myocardial infarction in China from 2001 to 2011 (the China PEACE-Retrospective Acute Myocardial Infarction Study): a retrospective analysis of hospital data. Lancet. 2015; 31: 385(9966): 441–451.
13. Nazif Aygut, Kurtulufl ozdemir, Adnan Abac et al. Prevalence of risk factors of ST segment elevation myocardial infarction in Turkish patients living in Central Anatolia. Anadolu Kardiyol Derg. 2009; 9: 3-8.
14. v on Eyben FE, Bech J, Madsen JK etal. High prevalence of smoking in young patients with acute myocardial infarction. J R Soc Health. 1996; 116(3):153–6.
15. R umboldt Z, Rumboldt M, Pesenti S etal. Peculiarities of myocardial infarction at young age in Southern Croatia. Car- diologia. 1995; 40(6):407–11.
16. Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol. 2004; 43(10):1731-7.
17. Muhammad S Khan, Fahim H Jafary, Azhar M Faruqui etal. High prevalence of lack of knowledge of symptoms of acute myocardial infarction inPakistan and its contribution to delayed presentationto the hospital. BMC Public Health. 2007, 7:284.
18. S tones PH, Muller JE, Hartwell T et al. The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: contribution of both coronary disease an diastolic left ventricular dysfunction to the adverse prognosis. J Am Coll Cardiol. 1989; 14:49.
19. Woods KL, Samanta A, Burden AC. Diabetes mellitus as a risk factor for myocardial infarction in Asians and Europeans. Heart. 1989; 62(2):118-22.
20. Singh PS, Singh G, Singh SK. Clinical profile and risk factors in acute coronary syndrome. J Ind Acad Clin Med. 2013; 14(2):130-2.
21. Hafeez S, Javed A, Kayani AM. Clinical profile of patients presenting with acute ST elevation myocardial infarction. J Pak Med Assoc. 2010; 60(3):190-3.